The hidden impact of slide choice on digital pathology:background staining, scanning efficiency, and data burden.
DESCRIPTION
Whole slide imaging (WSI) is gaining widespread adoption in diagnostic and research pathology. While attention is often given to image clarity and scanner performance, the microscope slide itself can be an
influential factor in digital pathology. Background staining, an artifact arising from residual stain retained on slide surfaces, can affect the efficiency and economics of digital scanning systems as it can introduce a non-tissue signal that scanners interpret as tissue.
This study evaluates the impact of background staining to whole slide image file size and scanning speed between 2 different brands of adhesion slides.
