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Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of...
Abstract Lin28 RNA-binding proteins are stem-cell factors that play key roles in development. Lin28 suppresses the biogenesis of let-7 microRNAs […]...
Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis...
Abstract Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs. Genetic, transcript...
Release of IFNɣ by Acute Myeloid Leukemia Cells Remodels Bone Marrow Immune Microenvironment by Ind...
Abstract Purpose: The stromal and immune bone marrow (BM) landscape is emerging as a crucial determinant for acute myeloid leukemia […]...
Characterization of a decellularized rat larynx: comparison between microscopy techniques...
Abstract Background: No effective method has yet been developed to efficiently reconstruct the larynx and restore its function. Decellularization has [&hel...
A cellular hierarchy in melanoma uncouples growth and metastasis...
Abstract Although melanoma is notorious for its high degree of heterogeneity and plasticity1,2, the origin and magnitude of cell-state diversity remains [...
Modulation of inflammatory M1-macrophages phenotype by valvular interstitial cells...
Abstract Background: Aortic valve stenosis involves inflammation, excess deposition of a collagen-rich extracellular matrix, and calcification. Recent stud...
Minimizing risk of iatrogenic nerve injury during peroneus longus tendon autograft harvest: a cadave...
Abstract Purpose: To evaluate the distances using ultrasound between the superficial peroneal nerve (SPN) and sural nerve along the peroneus […]...
Neuronal nitric oxide synthase positive neurons in the human corpus callosum: a possible link with t...
Abstract Brain functions have been investigated in the past decades via the blood-oxygen-level dependent (BOLD) effect using functional magnetic resonance ...
Ziwuliuzhu Acupuncture Modulates Glu/GABA‐Gln Metabolic Loop Abnormalities in Insomniac Rats...
Abstract Ziwuliuzhu acupuncture is widely considered an effective treatment for insomnia in clinics, but little is known about its possible […]...
Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahep...
Abstract Background: Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant tumor characterized by an intensive desmoplastic reaction due to the exag...
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