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Cyclodextrin microneedles for the delivery of a nanoparticle-based peptide antigen vaccin...

et al. Silvana Geisshusler...

European Jpouirnal of Pharmaceutics and Biopharmaceutics

Product: H&E

In recent years, microneedles (MNs) have gained considerable interest in drug formulation due to their non-invasive and patient-friendly nature. Dissolving...
Preclinical model of advanced prostate cancer...

et al. Rydell Alvarez-Arzola...

Cell Communication and Signaling

Product: H&E - Ottix

Androgen deprivation therapy (ADT) is a standard therapy for prostate cancer (PCa). Though disseminated disease is initially sensitive to ADT, […]...
Control mechanism of DC cells in tumors...

et al. Bayerl...

Immunity

Product: Antigenfix

Type 1 conventional dendritic cells (cDC1s) are critical for anti-cancer immunity. Protective anti-cancer immunity is thought to require cDC1s to […...
Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of...
Abstract Lin28 RNA-binding proteins are stem-cell factors that play key roles in development. Lin28 suppresses the biogenesis of let-7 microRNAs […]...
Protein homeostasis regulation in breast tumor resilience...

Varone...

British Journal of Pharmacology

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Endoplasmic reticulum (ER) stress triggers an adaptive response in tumours which fosters cell survival and resilience to stress. Activation of […]...
Mcl-1 proteins and their relation with senolytic therapy...

Martina Troiani...

Nature Communications

Product: Ottix - Hematoxylin - Eosin - Mounting Media - Citrate Buffer

Mcl-1 (Induced myeloid leukemia cell differentiation protein) is a protein that is encoded by the  MCL1  gene in humans. Cells sub...
The Role of micro-RNA in pleural mesothelioma...

Francesca Napoli...

Virchows Archive

Product: Silver impregnation

The Role of micro-RNA is a standard front-line treatment for pleural mesothelioma (PM) is pemetrexed-based chemotherapy, whose major target is […]...
Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain ...

Marina Scardigli, Luca Pesce and others ...

Frontiers in Neuroanatomy

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The combination of tissue clearing techniques with advanced optical microscopy facilitates the achievement of three-dimensional (3D) reconstruction of macr...
Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidati...

Johanna Merlin, Stoyan Ivanov, Adélie Dumont and others...

Research square

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Macrophages rely on tightly integrated metabolic rewiring to clear dying neighboring cells by efferocytosis during homeostasis and disease. Here we reveal ...
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis...

Ilaria Guccini,
 Ajinkya Revandkar,
 Mariantonietta D'Ambrosio,
Manuel Colucci,
Emiliano Pasquini,
Simone Mosole,
Martina Troiani,
Daniela Br...

Cancer Cell

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Metastases account for most cancer-related deaths, yet the mechanisms underlying metastatic spread remain poorly understood....

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