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A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection...
Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide, in whom virus-specific CD8 T cells by still ill-defined mechanisms [&he...
Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury...
Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent complication of diabetes and obesity, and […]...
Exploring multiple bioprocess monitoring modalities for Large-scale 3D Bioprinted Tissue Cultivation...
In tissue engineering (TE) and regenerative medicine (RM), challenges persist in achieving optimal tissue maturation due to uncontrolled physicochemical en...
Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ ...
Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) [&helli...
Venous-plexus-associated lymphoid hubs support meningeal humoral immunity...
There is increasing interest in how immune cells in the meninges—the membranes that surround the brain and spinal cord—contribute to […]...
Salicylic acid and RNA interference mediate antiviral immunity of plant stem cells...
Stem cells are essential for the development and organ regeneration of multicellular organisms, so their infection by pathogenic viruses must […]...
Mechanism for protective anticancer immunity...
Type 1 conventional dendritic cells (cDC1) can support T cell responses within tumors but whether this determines protective versus ineffective anti-cance...
IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance an...
Abstract IFNγ is an immune mediator with concomitant pro- and anti-tumor functions. Here, we provide evidence that IFNγ directly acts […]...
Soft gallstone-crushing robots...
Abstract The current treatment for symptomatic gallstones is primarily surgical, where one of the most general surgeries, laparoscopic cholecystectomy, is ...
Fibroblasts and lymph node homeostasis...
Abstract Emergent physical properties of tissues are not readily understood by reductionist studies of their constituent cells. Here, we show […]...
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