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Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vas...

et al. Guilhem R. Thierry...

Immunity

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Unlike sessile macrophages that occupy specialized tissue niches, non-classical monocytes (NCMs)—circulating phagocytes that patrol and cleanse the lumin...
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection...

et al. Miriam Bosch...

Nature

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Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide, in whom virus-specific CD8 T cells by still ill-defined mechanisms [&he...
The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects...

et al. Allison Carles...

CNS Neurosci Ther.

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Aims: Alzheimer’s disease (AD) is a devastating dementia characterized by extracellular amyloid-β (Aβ) protein aggregates and intracellular ta...
Cholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antige...

et al. Zi-Xun Yan...

Nature Communications

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Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell […...
Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury...

et al. Ayshwarya Subramanian...

Cell Reports

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Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent complication of diabetes and obesity, and […]...
17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3...

et al. Giulia Sbrini...

European Journal of Pharmacology

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Dopaminergic neurons express a heteromer composed of the dopamine D3 receptor and the α4β2 nicotinic acetylcholine receptor, the D3R-nAChR heteromer, [&h...
Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protectio...

et al. Shuaishuai Zhu...

iScience

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Tuning of protein homeostasis through mobilization of the unfolded protein response (UPR) is key to the capacity of pancreatic beta […]...
Exploring multiple bioprocess monitoring modalities for Large-scale 3D Bioprinted Tissue Cultivation...

et al. Laura Chastagnier...

Research Square

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In tissue engineering (TE) and regenerative medicine (RM), challenges persist in achieving optimal tissue maturation due to uncontrolled physicochemical en...
Pilocarpine-Induced Status Epilepticus in the Rat Hippocampus Is Associated with Reactive Glia and C...

et al. Grigorios Kyriatzis...

International Journal of Molecular Sciences

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Temporal lobe epilepsy (TLE) is associated with reorganization of hippocampal neuronal net-works, gliosis, neuroinflammation, loss of integrity of the bloo...
Confined biofabrication in inflatable bioreactor: toward the sterile production of implantable tissu...

et al. Alexandre Dufour...

Research Square

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The future of organ and tissue biofabrication strongly relies on 3D bioprinting technologies. However, maintaining sterility remains a critical issue [&hel...

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