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A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death...
In sepsis, limited food intake and increased energy expenditure induce a starvation response, which is compromised by a quick decline […]...
Tuning viscoelasticity and stiffness in bioprinted hydrogels for enhanced 3D cell culture: A multi-s...
Bioprinted hydrogels are extensively studied to provide an artificial matrix for 3D cell culture. The success of bioprinting hydrogels relies […]...
Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vas...
Unlike sessile macrophages that occupy specialized tissue niches, non-classical monocytes (NCMs)—circulating phagocytes that patrol and cleanse the lumin...
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection...
Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide, in whom virus-specific CD8 T cells by still ill-defined mechanisms [&he...
The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects...
Aims: Alzheimer’s disease (AD) is a devastating dementia characterized by extracellular amyloid-β (Aβ) protein aggregates and intracellular ta...
Cholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antige...
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell […...
Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury...
Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent complication of diabetes and obesity, and […]...
17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3...
Dopaminergic neurons express a heteromer composed of the dopamine D3 receptor and the α4β2 nicotinic acetylcholine receptor, the D3R-nAChR heteromer, [&h...
Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protectio...
Tuning of protein homeostasis through mobilization of the unfolded protein response (UPR) is key to the capacity of pancreatic beta […]...
Exploring multiple bioprocess monitoring modalities for Large-scale 3D Bioprinted Tissue Cultivation...
In tissue engineering (TE) and regenerative medicine (RM), challenges persist in achieving optimal tissue maturation due to uncontrolled physicochemical en...
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