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An extramedullary bone model to study metastatic dormancy reveals a piecemeal model for metastatic r...
Metastatic relapse can occur months to years after the cancer is first diagnosed, and it relies on the reactivation of […]...
Platelet-derived factors dysregulate placental sphingosine-1-phosphate receptor 2 in human trophobla...
Abstract Research question Sphingosine-1-phosphate (S1P) is an essential and bioactive sphingolipid with various functions, which acts through five differe...
Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse mod...
Severe acute malnutrition (SAM) is a multifactorial disease affecting millions of children worldwide. It is associated with changes in intestinal […...
Ex-vivo Expansion of Bone Marrow-derived Mesenchymal Stromal Cells for Clinical Use...
Abstract Background: In the last decades the replacement of fetal bovine serum (FBS) with human Platelet Lysate (hPL) for ATMPs […]...
Phagocyte targeting for immune response improvement...
Peyer’s patches (PPs) are secondary lymphoid organs in contact with the external environment via the intestinal lumen, thus combining antigen […]...
Control mechanism of DC cells in tumors...
Type 1 conventional dendritic cells (cDC1s) are critical for anti-cancer immunity. Protective anti-cancer immunity is thought to require cDC1s to […...
Study of unique parasite kinase as potential drug target...
Eimeria tenella is an obligate intracellular parasite responsible for avian coccidiosis. Like other apicomplexan parasites, such as Toxoplasma gondii, ce...
Mouse model for viral infection studies...
Plasmacytoid dendritic cells (pDCs) are the main source of type I interferon (IFN-I) during viral infections. Their other functions are […]...
Structure of 3D bioprinted dermis...
In recent years, numerous strategies have emerged to answer the growing demand for graftable tissues. Tissue engineering and in-vitro production are one ...
Mechanism for protective anticancer immunity...
Type 1 conventional dendritic cells (cDC1) can support T cell responses within tumors but whether this determines protective versus ineffective anti-cance...
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