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Downregulation of the Glo1 Gene...
Methylglyoxal (MG), a potent precursor of advanced glycation end-products (AGE), is increased in metabolic disorders such as diabetes and obesity. ...
Scleral ossicles: a biomaterial for medicine...
Given the current prolonged life expectancy, various pathologies affect increasingly the aging subjects. Regarding the musculoskeletal apparatus, bone frag...
Tea tree oil a new natural adjuvant for inhibiting glioblastoma growth...
Tea Tree oil (TTO), the essential oil from the Australian native Melaleuca alternifolia has demonstrated a variety of beneficial efficacies including antim...
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis...
Metastases account for most cancer-related deaths, yet the mechanisms underlying metastatic spread remain poorly understood....
Dysgerminoma – A Case Presentation...
Dysgerminomas are a type of ovarian tumour which are developed from the germinal tissue and have a frequency of approximately 2% of all ovarian cancers. We...
Synthetic progestin negatively affects mating behavior...
High rates of progestins consumption in the form of active ingredients in women's oral contraceptives and other hormonal preparations may lead to their inc...
Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibitio...
Tumor-associated macrophages (TAMs) represent a major component of the tumor microenvironment supporting tumorigenesis. ...
Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T ...
The NUP214-ABL1 fusion is a constitutively activated tyrosine kinase that is significantly associated with overexpression of the TLX1 and TLX3 transcriptio...
Multidrug resistance via simultaneous of cytostatic drug...
Multidrug resistance (MDR) is a common cause of failure in chemotherapy for malignant diseases. MDR is either acquired as a result of previous repeated exp...
Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Matur...
To identify the cells at the origin of melanoma, we combined single-cell lineage-tracing and transcriptomics approaches with time-lapse imaging....
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