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Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis...
Abstract Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs. Genetic, transcript...
Modulation of inflammatory M1-macrophages phenotype by valvular interstitial cells...
Abstract Background: Aortic valve stenosis involves inflammation, excess deposition of a collagen-rich extracellular matrix, and calcification. Recent stud...
Tissue tropism and infection of a symbiotic system...
Tissue tropism and infection are the main topic of this reasearch where they are observated in a symbiotic system. Dependence […]...
ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid response...
The hypothalamic-pituitary-adrenal (HPA) axis forms a complex neuroendocrine system that regulates the body’s response to stress such as starvation....
Rearing conditions and life history influence the progress of gametogenesis and reproduction perform...
Pikeperch (Sander lucioperca) is a highly valuable fish in Europe. However, development of aquaculture of pikeperch is highly limited due to seasonality of...
Macrophage Liver Imprinted by Stellate Cells...
Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific ident...
ZEB2, vital to Maintain the Tissue-Specific Identity...
Heterogeneity between different macrophage populations has become a defining feature of this lineage. However, the conserved factors defining macrophages r...
Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T ...
The NUP214-ABL1 fusion is a constitutively activated tyrosine kinase that is significantly associated with overexpression of the TLX1 and TLX3 transcriptio...
Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Matur...
To identify the cells at the origin of melanoma, we combined single-cell lineage-tracing and transcriptomics approaches with time-lapse imaging....
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