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Fibroblasts and lymph node homeostasis...

Horsnell...

Nature Immunology

Product: Antigenfix

Abstract Emergent physical properties of tissues are not readily understood by reductionist studies of their constituent cells. Here, we show […]...
SIGIRR Negatively Regulates IL-36 Inflammation...

Giannoudaki...

Journal of Immunology

Product: Citrate Buffer

SIGIRR has been described as a negative regulator of several IL-1R/TLR family members and has been implicated in several inflammatory […]...
Oral treatment of 4-methylumbelliferone reduced perineuronal nets and improved recognition memory in...

Dumisova...

Brain Research Bulletin

Product: Hematoxylin - Eosin

Hyaluronan (HA) is a core constituent of perineuronal nets (PNNs) that surround subpopulations of neurones. The PNNs control synaptic stabilization [&helli...
COVID-eVax, an electroporated DNA vaccine...

Antonella Conforti, Emanuele Marra and others...

Molecular Therapy

Product: Cristal Violetto

The COVID-19 pandemic caused by SARS-CoV-2 has made the development of safe and effective vaccines a critical priority. To date, four vaccines have been ap...
Mineralocorticoid Receptor Antagonists Eplerenone and Spironolactone Modify Adrenal Cortex Morpholog...

Sofia S. Pereira, Liliana Carvalho, Madalena M. Costa and others...

MDPI biomedicines

Product: Cresyl Violet

Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act by blocking aldosterone action. The aim of this study was to ...
Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibitio...

Diletta Di Mitri, Michela Mirenda, Jelena Vasilevska, Arianna Calcinotto, Nicolas Delaleu, Ajinkya Revandkar, Veronica Gil, Gunther Boysen, Marco Losa, Sim...

Cell Reports

Product: Ottix - HE

Tumor-associated macrophages (TAMs) represent a major component of the tumor microenvironment supporting tumorigenesis. ...
Macrophage Liver Imprinted by Stellate Cells...

Johnny Bonnardel, Wouter T’Jonck, Djoere Gaublomme, Robin Browaeys, Charlotte L. Scott, Liesbet Martens, Bavo Vanneste, Sofie De Prijck, Sergei A. Nedosp...

Immunity

Product: Antigenfix

Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific ident...
Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion...

Victor G. Martinez, Valeriya Pankova, Lukas Krasny, Tanya Singh, Spyridon Makris, Ian J. White, Agnesska C. Benjamin, Simone Dertschnig, Harry L. Horsnell,...

Cell

Product: Antigenfix

Lymph nodes (LNs) act as filters, constantly sampling peripheral cues. This is facilitated by the conduit network, a tubular structure of aligned extracell...
ZEB2, vital to Maintain the Tissue-Specific Identity...

Charlotte L. Scott and others....

Immunity

Product: Antigenfix

Heterogeneity between different macrophage populations has become a defining feature of this lineage. However, the conserved factors defining macrophages r...
NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Contr...

Jan P. Böttcher, Eduardo Bonavita, Probir Chakravarty, Hanna Blees, Mar Cabeza-Cabrerizo, Stefano Sammicheli, Neil C. Rogers, Erik Sahai, Santiago Zelenay...

Cell

Product: Antigenfix

Conventional type 1 dendritic cells (cDC1) are critical for antitumor immunity, and their abundance within tumors is associated with immune-mediated reject...

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